New Sign-in Time - 11:30am Due to Weather! - Dana's Angels Research Trust's 2023 "DART To The Finish" 2 Mile Walk to Cure Niemann-Pick type C Disease - Registration Fees are tax deductible donations

• Sign up for this year's DART TO THE FINISH Charity Walk - In-Person or Virtual.
  

• Once your registration is complete, you will receive a unique referral link to share with your friends, family or post on social media

• Get 4 Adult (22 yo+) or 8 Youth (10-21 yo) friends to sign up using your unique referral link and you will automatically receive a gift certificate of $25.00 to Amazon shopping or your choice of one of our local restaurants; each of whom has been a generous supporter of DART over the years.

• Get 8 or more Adult friends or 15 Youth friends to sign up using your unique referral link and you will automatically receive a second gift certificate of $25.00 to Amazon shopping or your choice of one of the local restaurants.

• Keep Sharing and Promoting your link.

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Dana’s Angels Research Trust is a non-profit organization that funds research into a rare disease, Niemann-Pick type C (NPC), a fatal, cholesterol-storage disease affecting children.  Two of the Marella’s four children, Dana and Andrew, were afflicted by NPC.  Most children who suffer from NPC die in their early teens, but DART has helped change that fate.  As an all-volunteer organization, over 95% of the funds expended are channeled directly into supporting pivotal NPC research; research that may also help millions of people suffering from HIV/Aids, Ebola, heart disease, stroke, Alzheimer’s disease  and other disorders that appear to be related to cholesterol.

Sadly, the Marella’s daughter, Dana, 19, passed away in the Summer of 2013. When Dana died, she was confined to a wheelchair, no longer talked, suffered from frequent pneumonia and required constant care, but she always had a smile on her face and was an inspiration to many, both here and around the world.  The Marella’s youngest child, Andrew, who turns 24 on June 3, 2023, is relatively stable right now, although with the passing of his sister, Andrew struggles with seizures.  Andrew has benefited from two experimental medications, all due in large part to the supporters of DART.

Niemann-Pick type C (NPC) is a rare genetic disease.  But there is strong interest in studying NPC from researchers in many fields because of its connection to cholesterol metabolism.  Research has shown that studying NPC may unlock the mysteries related to more common diseases affecting millions.

HIV/AIDS and Ebola:  The NPC protein is critical for the normal trafficking of cholesterol in all of the cells in our bodies.  Research shows that chemical creation of the NPC defect in diseases like HIV and Ebola results in drastically reduced infection, indicating that the NPC protein associated with cholesterol trafficking is required for infection.

Alzheimer’s:  Alzheimer’s and NPC are progressive neurological diseases with similar effects on the brain.  Recent studies comparing the two diseases discovered that Alzheimer’s is closely tied to a failure in cholesterol metabolism – the very process that is central to NPC.

Heart Disease and Stroke:  We all know that high cholesterol is the main cause of heart disease and stroke.  But until the gene that causes NPC was discovered, researchers had few opportunities to identify the complex processes that regulate cholesterol.  How does the body know if it has too much cholesterol or too little?  NPC research is beginning to provide answers.

PDF of Walk Course Below.

Click the icon below to download the attached PDF.